A: The HeatStroke Kit Test is a research-use diagnostic tool designed to detect early signs of kidney stress caused by heat stroke and dehydration. It measures L-FABP (Liver-type Fatty Acid Binding Protein) in urine, enabling timely intervention to prevent acute kidney injury (AKI) and long-term kidney damage.
A: L-FABP is a low molecular weight soluble protein (14 kDa) specifically expressed in the liver and renal proximal tubules. Under conditions like renal tubular ischemia and oxidative stress, L-FABP is excreted into urine, making it a useful marker for early diagnosis of renal diseases associated with tubular dysfunction.
A: The test detects L-FABP in urine, which is released from kidney tubular cells under stress. Elevated levels indicate kidney stress before symptoms appear, allowing for early intervention to prevent serious complications.
A: The kit is intended for research use with populations exposed to extreme heat, including:
It is not for home or clinical diagnostic use.
A: The assay time is approximately 2 hours, from sample collection to result interpretation.
A: A standard urine sample is collected in a clean container and added to the test according to the kit instructions. No special preparation is needed.
A: The kit cannot prevent damage directly, but by detecting stress early, it allows researchers, safety officers, and healthcare teams to implement interventions (hydration, rest, medical monitoring) that reduce the risk of AKI and long-term complications.
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A: The HeatStroke Kit Test is for research use only. It is not approved for clinical diagnosis or treatment decisions.
A: For research and clinical references, see peer-reviewed publications on L-FABP as an early biomarker of kidney stress and studies on heat stroke-related acute kidney injury (AKI). Your kit supplier can provide a curated list of key studies.